

Typically, access is provided across an institutional network to a range of IP addresses. If you are a member of an institution with an active account, you may be able to access content in one of the following ways: Get help with access Institutional accessĪccess to content on Oxford Academic is often provided through institutional subscriptions and purchases. Finally, the chapter considers an emerging area of investigation in normal function and in disease: molecular and developmental mechanisms regulating dendritic form, the targets upon which selection has acted. These observations are consistent with the unifying principle that dendrites have adapted to keep circuit-level function the same, even though per-gram metabolic rates vary widely. Dendritic spines may have originated to form and regulate connections, and later acquired the function of maximizing information storage in densely packed neuropil. The evidence that dendrites scale across phylogeny to preserve the number of synapses per neuron is reviewed, as well as the architecture of local microcircuits, including the number of neurons in a single neocortical column.

This chapter explores this diversity to consider dendrites from an evolutionary perspective. The great diversity of dendrites, both within individual species and across phylogeny, reflects their adaptation to particular functional roles.

Dendrites, the neuronal processes that receive synaptic inputs, are found in all nervous systems.
